Chemistry 516

Course Objective: The relationship among topics in organic chemistry will be explained.

Organic Spectroscopy

Student Learning Outcomes: Upon completion of the course, the student will be able to:

· Describe the basic instrumental principles involved in the operation of mass spectrometers, infrared spectrometers, and nuclear magnetic resonance spectrometers. This includes methods of sample handling and preparation, signal generation and detection, and data analysis for each method.

· Describe the physical and chemical principles that occur at the molecular level during a MS, IR, or NMR experiment.

· Analyze MS, IR, and/or NMR spectral data (either alone or in combination) to elucidate the structure of an organic molecule. This includes being able to make correlations of spectral features to specific portions of a molecule’s structure.

Advanced Organic Mechanisms

Student Learning Outcomes: Upon completion of the course, the student will be able to:

· Use the principles of quantum mechanics and molecular orbital theory to describe specific aspects of molecular structure and reactivity

· Use molecular orbital theory to explain the products of pericyclic reaction processes

· Use data from physical methods (e.g. stereochemical experiments, kinetic isotope effects, and linear free-energy relationships) to explain the mechanism of an organic reaction

· Use mechanistic principles to propose reasonable stepwise mechanisms for an organic reaction (including reactions of heterocyclic compounds and bioorganic compounds)

Organometallic Chemistry

Student Learning Outcomes: Upon completion of the course, the student will be able to:

· Use the basic principles of descriptive chemistry and molecular orbital theory to describe chemical bonding and structure of organometallic compounds

· Explain and predict the chemical behavior and reactivity of organometallic compounds

· Describe and explain catalytic processes using an organometallic compound as a catalyst

· Show and explain how organometallic compounds are used as catalysts in organic synthesis

· Describe physical characterization methods used to study the structure and behavior of organometallic compounds